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What is Cocarboxylase?

Cocarboxylase, also known as thiamine pyrophosphate (TPP) or thiamine diphosphate, is the active form of vitamin B1 (thiamine). It serves as a coenzyme in various biochemical reactions within the body, particularly in carbohydrate metabolism.

Health benefits of using Cocarboxylase

1. Supports Energy Production:

Cocarboxylase plays a crucial role in converting carbohydrates, particularly glucose, into usable energy (ATP) through metabolic pathways like the citric acid cycle. Adequate levels of cocarboxylase help the body efficiently generate energy from food.

2. Metabolic Support:

Cocarboxylase is involved in various enzymatic reactions related to metabolism. It assists in breaking down sugars and amino acids and is vital for overall metabolic function.

3. Heart Health: 

Adequate levels of thiamine and its active form cocarboxylase support cardiovascular health indirectly through their roles in energy metabolism. They help ensure the heart has sufficient energy to function optimally.


Cocarboxylase's role as an active coenzyme in essential metabolic processes and nervous system function underscores its importance for overall health and well-being. Ensuring an adequate intake of thiamine-rich foods or supplements containing cocarboxylase helps support these vital functions. However, it's important to consult with a healthcare professional before starting any new supplement, especially for individuals with existing health conditions or who are pregnant or breastfeeding.

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